Interbreeding and fecundity of a single pair of two strains of Trichinella spiralis in mice.

Amelioration of Myogenin, Bcl-2 expression and DNA damages in myocytes of Trichinella spiralis-infected mice after immunization with gamma radiation-attenuated larvae

Background: In trichinosis, the presence of muscle larvae inside skeletal striated muscle causes loss of identity and function of myotube through the releasing of myogenin and myosin. Considering the dominant role of vaccination, research on gamma radiation-attenuated vaccine has very promising value. The goal of this study was to determine the efficacy of vaccination with radiation-attenuated ...

A single gene determines rapid expulsion of Trichinella spiralis in mice.

In rats and some inbred mouse strains, one immune response, rapid expulsion, confers up to 95% protection against a challenge infection with Trichinella spiralis. Strain analysis in mice has shown that only three inbred strains, all originating from Swiss-line mice at the National Institutes of Health, Bethesda, Md., express rapid expulsion. Crosses between responder strain mice (NFR/N) and non...

Longevity and fecundity of Trichinella spiralis in mast cell-deficient Sl/Sld mice.

Detection by polymerase chain reaction of Trichinella spiralis larvae in blood of infected patients.

Detection of the repetitive sequence pPra specific for Trichinella spiralis was carried out by PCR in the blood of 37 patients infected tout to six weeks previously, during a horse-meat related outbreak of trichinellosis (Paris, 1993). Only two patients of 37 wete PCR-positive. Human blood was sampled during the febrile phase of the disease, before any antihelminthic treatment. To assess the va...

Therapeutic Potential of Myrrh and Ivermectin against Experimental Trichinella spiralis Infection in Mice

Trichinosis is a parasitic zoonosis caused by the nematode Trichinella spiralis. Anthelmintics are used to eliminate intestinal adults as well as tissue-migrating and encysted larvae. This study aimed to investigate the effects of ivermectin and myrrh obtained from the aloe-gum resin of Commiphora molmol on experimental trichinosis. Ninety albino mice were orally infected with 300 T. spiralis l...